Zur pathologischen Anatomie der Neuromyelitis optica

Grundriss der pathologischen Anatomie

This is an enlarged and improved version of the first edition of the book. The author modestly disclaims originality for his work, which is not designed to replace the larger and more comprehensive treatises on Pathology, but to present to the student and learner in pathology the main facts of the science in as comprehensive a manner as is consistent with a treatment of the subject within a mod...

Anatomie des Wahnsinns. Geisteskrankheit im medizinischen Denken der frühen Neuzeit und die Anfänge der pathologischen Anatomie

Traditional historians of psychiatry have often argued that in medieval and in early modern times madness was interpreted in theological rather than in medical categories. According to this view, it was not before the seventeenth-century rivalry between religious and secular explanations that a rationalization and naturalization of madness took over. And even then, psychiatric knowledge was mai...

Beiträge zur Pathologie und pathologischen Anatomie des Centralnervensystems

Neuromyelitis Optica

An 11-year-old girl developed sudden visual loss in her left eye, preceding subacute myelitis by 9 months. Multifocal lesions in the central nervous system were demonstrated by magnetic resonance imaging. Although unilateral blindness is unusual, the clinical findings predominantly involving the optic nerve and spinal cord were consistent with the diagnosis of neuromyelitis optica (NMO). This c...

Treatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate

BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...